Thursday, January 19, 2012

Let the tax season begin!

Tina Fineberg / AP File

Remember when we used to fill out tax forms by hand? For most people, tax time now means turning on the computer. The IRS announced Wednesday that you can begin e-filing your returns, marking the start of tax season.

By Allison Linn

If you?re snowed in in Seattle or enjoying an extra long holiday weekend elsewhere in the country, here?s a nice way to spend the rest of the day: Filing your taxes.

The Internal Revenue Service announced Tuesday that it has begun accepting electronically filed tax returns for the 2012 tax year.

Most Americans already file individual tax returns electronically, and the government is hoping to increase that percentage even more in the coming years.

Of course, many people will probably wait much longer to file their tax returns, expecially this year. That?s because the tax deadline has been extended to April 17.

?

Source: http://bottomline.msnbc.msn.com/_news/2012/01/17/10176360-let-the-tax-season-begin

emergency alert system 21 jump street 19 kids and counting 2011 election results 11/11/11 11 11 11 activision blizzard

Multicellular Life Evolves In Months, In a Lab

I suspect it's not "evolution" at all, but subtly bad science (i.e. a scientist gunning for more grant money). DNA can express in many ways given varying environmental conditions, without the mutations that characterize true evolution -- and artificially forcing genetic drift by selecting for the bottom-clumpers is certainly VERY DIFFERENT from having gravity serve as the "selection pressure."

It's well known DNA can express in many different ways without true evolution. We've come a long way from the theory of Lamarckian evolutionary theory (evolution of acquired characteristics). One is example: exons, which can express differently across generations based on environmental conditions-- without actual change to the DNA.

I'm thinking this great discovery will get pounded upon by other biologists pretty quickly -- and put in its proper place as an interesting science experiment that really does not advance the field much if at all. INTERESTING evolution would be a group of mutations that lead to a multicellular outcome. That's NOT what these guys 1) demonstrated happened (multicellular DNA base-pair-causing mutations) or 2) proved was the actual genetic cause at the molecular-biology level.

IAAMBP (I am a molecular biophysicist) and I actually just finished discussing this article at work before seeing it on/. The parent post is an odd mix of insightful comments and flamebait so I'll respond to the former. BTW the actual research article itself is free for everyone to read, thanks to the authors shelling out an extra 1K$ to allow public access. I'll link it below:

http://www.pnas.org/content/early/2012/01/10/1115323109.full.pdf+html [pnas.org]

If you would prefer having to pay 10-30$ for the privilege of reading what your tax dollars already paid for instead of this commie "open access" stuff, please call your congressman and tell him/her to support HR bill 3699.

To contextualize this work: the path that led from single-celled eukaryotes to multicellular organisms is one of those $64,000 questions in evolutionary biology, that weird crossover from outright competition to coordinated teamwork. The advantages of being multicellular really pay off for big, complex organisms, but why on earth would it have been advantageous for a small group of a few dozen cells? This paper does not answer the question by any stretch, but it does provide a few interesting, unexpected clues. Most groups asking this question focus on Volvocine algae, which evolved multicellularity so recently such that you can compare them side by side with their nearly identical single-celled cousins in the very same pond. But these are not the most convenient organisms to work with; they have a very complicated life cycle, and have a monster-sized genome for their diminutive size (~140 million bases) and doing genetics on such beasties is still quite difficult and tedious.

Yeast, on the other hand, are really easy to work with and are actually pretty boring in most respects; ~12 million base pairs which have all been sequenced many times over. You can actually custom order them with any gene you want deleted just to see what happens, it's that well characterized. So the observation that artificially selecting for clusters in boring yeast leads to weird snowflake-shape colonies with something that resembles "programmed cell death" in higher organisms is completely unexpected an novel. "Programmed cell death" literally means that the colony has found a way to promote what's good for the colony over what's good for the individual, even though these are only 60 days removed from being a pretty ordinary yeast.

Is this how it happened billions of years ago? Probably not, this is just boring yeast after all, and I can't think of a scenario where sinking to the bottom is a life-or-death advantage. In the case of the algae, it would in fact be suicidal to sink beyond where the

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/1dnl9L12OjA/multicellular-life-evolves-in-months-in-a-lab

dc universe online hillary clinton digestive system solon rhetoric npr supernova

Wednesday, January 18, 2012

Aston Martin opens store in China

Recommended 2 times

Recommend it

Aston Martin continues its growth in the Chinese market with the opening of a flagship store

Aston Martin has continued its impressive investment and growth in the Far East with the opening of its largest flagship store, in the Pudong district of Shanghai.

The showroom has room for up to 18 new Aston Martins, as well as offering complete service with a caf?, lounge, Aston Martin merchandise display, sales area, fully equipped service centre, Jaeger-LeCoultre time-pieces and Bang & Olufsen audio/visual displays.

This is the seventh dealership to open in China for Aston Martin and the third owned and managed by Mr Zheng Ting.

Dr Matthew Bennett, Asia Pacific regional director, said: "We are excited with Aston Martin's ongoing development and performance in China. This wonderful new dealership sets the benchmark for luxury car showrooms across Asia and the experience each and every visitor should expect.

"With our existing China network of experienced Aston Martin dealerships, further future growth earmarked across the coming year and a number of exciting product developments to be announced during 2012, our China business is expected to continue growing strongly."

Copyright Press Association 2012

Source: http://www.rac.co.uk/news-advice/motoring-news/post/2012/1/aston-martin-opens-store-in-china/

tyson chandler best ipad apps chris paul chicago bulls carmelo anthony david lee gift card exchange